No physical tsunamigenic evidence from the 363 CE Cyril Quakes has been conclusively identified in the Dead Sea. However, Jerome in Commentariorum In Esaiam relays oral reports from Areopolis describing a seiche in the Dead Sea generated by one of the 363 CE Cyril Quakes. Although Jerome appears to have conflated these reports with Mediterranean tsunamis associated with the 365 CE Crete earthquake, this does not warrant dismissal of the Dead Sea account. The report may preserve genuine evidence of a seiche, and the associated seismites merit further geological investigation for possible tsunamigenic signatures.