During the 12th century CE,
Zardana,
located between Antioch and Aleppo, was a significant fortress town and changed hands several times between various Muslim powers
and the Crusaders. At times Zerdana and Atarib marked the eastern frontier of the Principality of Antioch.
The decisive battle known as Ager Sanguinis ("Field of Blood") was fought near Zaradana in 1119 CE and the town was
badly damaged during the
1138 CE Aleppo Quake.