Darayya is a settlement immediately southwest of Damascus and is mentioned by two later Syriac chroniclers, Michael the Syrian and Chronicon Ad Annum 1234, both of whom report exceptionally heavy loss of life during the earthquake sequence of January 749 CE. These two accounts are not independent, as the Chronicon Ad Annum 1234 and Michael the Syrian are thought to have shared many sources, and there are strong similarities in their descriptions of this earthquake sequence.

Rather than describing specific collapsed buildings in Darayya, both chroniclers emphasize the human toll. Michael the Syrian reports that "myriads of people died" there, while the Chronicon Ad Annum 1234 likewise states that "countless people died" in "Gutah [a suburb] of Dareya." In the same passages they compare this destruction with severe earthquake damage reported elsewhere in southwestern Syria, including the collapse of a fortress at Beit Qoubayê in which more than eighty people were killed, prolonged strong shaking in Damascus, and the devastation of Bosra, Nawa, and Ghouta. Because the sources appear to treat Darayya and the Ghouta together, it is uncertain whether the reported fatalities refer to the town itself or to the surrounding suburban and rural districts adjacent to Damascus.

The earthquake responsible for the reported destruction cannot be identified with certainty. Because Darayya lies immediately southwest of Damascus, the damage most likely resulted from the Holy Desert Quake North, although attribution to the Talking Mule Quake cannot presently be excluded.